Beta-blockers in hypertension: adding insult to injury.
نویسنده
چکیده
eta-blockers have been found not to be effective for rimary prevention of cardiovascular disease in patients with rimary hypertension. The problem was first recognized by esserli et al. (1) in 1998. They pointed out the signifiantly lesser benefit of beta-blocker therapy in 2 trials versus iuretic-based therapy in 7 separate trials. Their presentaion could not have been clearer: “Diuretic therapy was uperior to blockade with regard to all end points. . . -blocker therapy only reduced the odds for cerebrovascular vents but was ineffective for preventing coronary heart isease, cardiovascular mortality and all-cause mortality.”
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عنوان ژورنال:
- Journal of the American College of Cardiology
دوره 52 18 شماره
صفحات -
تاریخ انتشار 2008